Krill Oil Research

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Krill Oil from Neptune , NKO® The ultimate Omega 3 Fish Oil

Neptune Krill Oil is proven to be effective with successful human testing, with:

• - Cholesterol study demonstrates a 34% reduction in LDL and a 44%  increase in the good fats HDL
• - Chronic Joint Inflammation – Phase II study – 20% reduction
• - PMS study shows a 42% improvement (both physical and emotional symptoms)
• - Health Benefits of Omega-3 Fatty Acids from Neptune Krill Oil 

Cholesterol Reduction

Krill Oil NKO® is effective in controlling hyperlipidemia by significantly reducing total cholesterol levels, LDL (bad cholesterol) and triglycerides, while increasing HDL (good cholesterol) to as yet unmatched levels.  Please see results (Phase III a) tests.

Reducing Cholesterol

There are several predictors of the risk of cardiovascular disease; with  high levels of total cholesterol, LDL cholesterol, and triglycerides, and low levels of "good" HDL cholesterol all are long-standing indicators of risk of coronary heart disease.

Krill Oil NKO was the subject of a controlled human study involving 120 patients with hyperlipidemia (elevated blood lipids ie Cholestero ). The study included groups receiving placebo, receiving 3 g fish oil daily, and those receiving 1 g, 1.5 g, 2 g, 3 g NKO Krill Oil daily for 90 days.

After ninety days, all NKO Krill Oil groups showed significant decreases in total cholesterol, LDL cholesterol, and triglycerides, and simultaneous increases in HDL cholesterol. In the 1g and 1.5 g Krill Oil groups, the patients were kept on a maintenance dose of 500 mg daily for another ninety days, and each group maintained significant corrections in all four markers as compared with baseline.

 Krill Oil NKO™ V’s Fish Oil Percentage Change in Cholesterol

Conclusion

The results of this clinical trial demonstrated that daily doses of 1-3g krill oil are significantly more effective than 3g EPA/DHA fish oil in the management of hyperlipidemia.  Furthermore, a maintenance dose of 500mg krill oil is significantly effective for long-term regulation of blood lipids. The unique molecular composition of krill oil, which is rich in phospholipids, omega-3 fatty acids, and diverse antioxidants, surpasses the profile of fish oils and offers a superior approach towards the reduction of risk for cardiovascular disease.

Reference:  Alternative Medicine Review, Volume 9, No 4, 2004

Chronic Inflammation and Osteoarthritis

Krill Oil NKO® can significantly reduce the C-Reactive protein and osteo-arthritic symptoms in patients diagnosed with a chronic inflammation disease. (Phase II)

Krill Oil NKO has been shown to significantly decrease elevated C-reactive protein levels in a controlled human study. The study involved 90 patients, 45 receiving 300 mg of NKO Krill Oil daily,   45 receiving a placebo. There was over a 30% mean decrease in C-reactive protein levels in the Krill Oil NKO™ group after 30 days.6

Effects of supplementation with Krill Oil NKO™ on Biomarkers of Chronic Inflammation

Reference:  Evaluation of the Effects of NKOtm on Biomarkers of Chronic Inflammation In Vivo, JSS Medical Research Inc., 2004

Reduction in Pain Scores by supplementation of Krill Oil NKO™ V’s Placebo

Reduction in Stiffness scores per visit (WOMAC) with supplementation of Krill Oil NKO™ vs Placebo

Conclusion

The results of the study indicate that Krill Oil NKO™ at a daily dose of 300 mg, can, within 7-14 days:

• Significantly inhibit inflammation by reducing C-Reactive Protein (CRP)
• Alleviate symptoms caused by osteoarthritis and rheumatoid arthritis.

Reference:  Evaluation of the Effects of NKOtm on Biomarkers of Chronic Inflammation In Vivo, JSS Medical Research Inc., 2004

Premenstrual Syndrome

Krill  Oil NKO® can significantly reduce the physical and emotional symptoms associated with PMS (premenstrual syndrome).

Reduction of Premenstrual Syndrome (PMS) 

Another study conducted on Krill Oil involved Premenstrual Syndrome (PMS). In a controlled published study, 70 patients with PMS were asked to take either 2 g NKO Krill Oil or 2 g of 18:12 fish oil daily for 30 days, then continue dosing eight days prior to and two days after menstruation, for a total study time of three months.

After both 45 and 90 days, there was a greater statistically significant improvement over a broader range of PMS symptoms in the NKO Krill Oil Group over the group taking fish oil. Symptoms improved by NKO Krill Oil included breast tenderness, stress, irritability, depression, joint pain, abdominal pain, weight gain, and bloating.

Conclusion

NKO can considerably reduce Dysmenorrhea and the emotional symptoms of Premenstrual Syndrome and is shown to be significantly more effective for the complete management of Premenstrual symptoms compared with omega-3 fish oil.

Alternative Medicine Review 2003:8(2) –171-179

Attention Deficit and Hyperactivity Disorder (ADHD)

The clinical results obtained during an open label pilot study demonstrated that NKO® may significantly improve cognitive function (among others concentration, planning skills and focus) of adults suffering from ADHD. 

Krill Oil NKO™ natural Ingredients per 1000mg    
 
Neptune Krill Oil contains:
100 IU of Vitamin A
400 mg of Phospholipids
90 mg of DHA
150 mg of EPA
85 mg of omega-9 fatty acids
73 mg of Choline
20 mg of omega-6 fatty acids
1.5 mg of Astaxanthin

Each bottle of Krill Oil NKO™ contains 60 capsules (500 mg each).  
 
Neptune Krill Oil contains no yeast, dairy, egg, gluten, soy, wheat, sugar, starch, salt, preservatives, artificial colour, artificial flavours, or fragrance.  
 
Note: If you are pregnant, nursing, allergic to shellfish, have a blood coagulation condition, or are taking anticoagulation’s such as Warfarin, consult your health care professional before using this product.  
 
The Food & Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease. 

Research Sources 

1.  ORAC Assay, Neptune Technologies and BioRessources, Nov 2003.  
2.  Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6,   Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academy Press, 1998, p. 390  
3.  Christopher L., "C-Reactive Protein," (Review) Medline Plus, US National Library of Medicine 4. Pasceri V, et al, "Direct Pro-Inflammatory Effect of C-Reactive Protein on Human Endothelial Cells," Circulation, 2000 Oct 102 (18): 2165-8.  
5.  Paoletti R., et al, "Inflammation in Atherosclerosis and Implications for Therapy." Circulation, 2004 Jun 109 (23 Suppl 1): 1120-6.  
6.  Sampalis F, unpub clinical study, 2004.  
7 . Bunea R, et al, unpub clinical study, 2004.  
8.  Sampalis F, Alternative Medicine Review, pp. 175-176.
9   Evaluation of the Effects of  Krill Oil NKO™  on Biomarkers of Chronic Inflammation In Vivo, JSS Medical Research Inc., 2004

 Team Nutrition April 2011

How Krill Oil Works Research study into the workings of Krill oil.

Bio Availability About Bio Availability of Krill v's Fish Oil

Krill Oil Capsules Capsules.